The one-in-four statistic is for miscarriages after the sixth week of pregnancy. In the general population, the percentage of miscarriages is 15%, or about one-in-six.
One thing to keep in mind is that a miscarriage is not the end of the world. Heartbreaking, yes, but it's not too late to try again.
I think that the word "miscarriage" carries extreme connotations with it, you instantly imagine giving birth to a dead baby.
In Germany, if a fetus or embryo does not continue development at an early-ish stage and is expelled by the womb, midwives (I used to date one for 2 years) usually use the word "Schwangerschaftsabbruch", which translates to "discontinuation of pregnancy".
I think that's a word which much better describes what's happening without the emotional baggage and which might prepare people better to what's going on - my girlfriend is 37 and we're trying to have kids but it's hard, and I know that we're going to run into a few "discontinuations" before anything is going to happen.
One thing to keep in mind is that a miscarriage is not the end of the world. Heartbreaking, yes, but it's not too late to try again.